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1.
Cien Saude Colet ; 28(3): 771-784, 2023 Mar.
Artículo en Portugués, Inglés | MEDLINE | ID: covidwho-2325904

RESUMEN

The article aims to estimate the incidence and worsening of back pain (BP) during the first wave of COVID-19 in Brazil, as well as to investigate demographic, socioeconomic factors and associated changes in living conditions. ConVid - Behavior Research, applied between April and May 2020, was used as data source. The number and distribution of respondents who developed BP and those who had a worsening of the preexisting problem, their 95% confidence intervals and Pearson's Chi-square test were estimated. The odds ratio of developing BP or worsening a preexisting problem was also estimated using multiple logistic regression models. Pre-existing BP was reported by 33.9% (95%CI 32.5-35.3) of respondents and more than half (54.4%; 95%CI 51.9-56.9) had worsened. The cumulative incidence of BP in the first wave of the pandemic was 40.9% (95%CI 39.2-42.7). Being a woman, the perceived increase in housework and the frequent feeling of sadness or depression were associated with both outcomes. Socioeconomic factors were not associated with any of outcome. The high incidence and worsening of BP during the first wave reveal the need for studies in more recent periods, given the long duration of the pandemic.


O artigo tem como objetivo estimar a incidência e o agravamento do problema de coluna (PC) durante a primeira onda da COVID-19 no Brasil, bem como investigar os fatores demográficos, socioeconômicos e as mudanças nas condições de vida associadas. Utilizou-se a ConVid - Pesquisa de Comportamentos, realizada entre abril e maio de 2020, como fonte de dados. Estimou-se o número e a distribuição dos entrevistados que desenvolveram PC e a dos que tiveram agravamento no problema preexistente, seus intervalos de 95% de confiança e o teste qui-quadrado de Pearson. Estimou-se também a razão de chance de desenvolver PC ou ter piora de problema preexistente por meio de modelos de regressão logística múltipla. O PC preexistente foi reportado por 33,9% (IC95% 32,5-35,3) dos entrevistados e mais da metade (54,4%; IC95% 51,9-56,9) teve piora do quadro. A incidência cumulativa de PC na primeira onda da pandemia foi de 40,9% (IC95% 39,2-42,7). Ser mulher, o aumento percebido do trabalho doméstico e o sentimento frequente de tristeza ou depressão foram associados a ambos os desfechos. Os fatores socioeconômicos não foram associados a nenhum dos desfechos. A alta incidência e agravamento do PC durante a primeira onda revelam a necessidade de estudos em períodos mais recentes, dada a longa duração da pandemia.


Asunto(s)
Dolor de Espalda , COVID-19 , Femenino , Humanos , Dolor de Espalda/epidemiología , Dolor de Espalda/etiología , Brasil/epidemiología , COVID-19/epidemiología , Incidencia , Modelos Logísticos
2.
Am J Case Rep ; 23: e937517, 2022 Oct 06.
Artículo en Inglés | MEDLINE | ID: covidwho-2056390

RESUMEN

BACKGROUND Streptococcus oralis (S. oralis) is a gram-positive bacterium and component of the oral microbiota that can rarely cause opportunistic infection in the immunosuppressed. This report presents a 60-year-old man from Hong Kong with gingivitis and poorly controlled diabetes who visited his chiropractor with low back pain 2 weeks following mild COVID-19 and was diagnosed with paraspinal, psoas, and epidural abscess due to S. oralis. CASE REPORT The patient tested positive for COVID-19 when asymptomatic, then had a mild 10-day course of the illness, followed by low back pain 1 week later, prompting him to visit his primary care provider, who diagnosed sciatica and treated him with opioid analgesics. He presented to a chiropractor the following week, noting severe low back pain with radiation into the gluteal regions and posterior thighs, difficulty with ambulation, and mild neck pain. Considering the patient's diabetes, widespread symptoms, and weakness, the chiropractor ordered whole-spine magnetic resonance imaging, which suggested possible multifocal spinal abscess and referred him urgently to a spine surgeon. The surgeon conducted testing consistent with bacterial infection, and referred to an infectious disease specialist, who confirmed S. oralis spinal infection via lumbar paraspinal needle biopsy and culture. The patient was first treated with oral antibiotics, then intravenous antibiotics in a hospital. Over 4 weeks, his spinal pain improved, and laboratory markers of infection normalized. CONCLUSIONS This case illustrates an opportunistic pyogenic spinal infection including paraspinal, psoas, and epidural abscesses caused by S. oralis in an immunocompromised patient following COVID-19 illness.


Asunto(s)
COVID-19 , Diabetes Mellitus , Absceso Epidural , Gingivitis , Dolor de la Región Lumbar , Analgésicos Opioides , Antibacterianos/uso terapéutico , Dolor de Espalda/etiología , Diabetes Mellitus/tratamiento farmacológico , Absceso Epidural/diagnóstico , Absceso Epidural/microbiología , Gingivitis/complicaciones , Gingivitis/tratamiento farmacológico , Humanos , Dolor de la Región Lumbar/etiología , Masculino , Persona de Mediana Edad , Streptococcus oralis
4.
Int Arch Occup Environ Health ; 95(2): 527-538, 2022 03.
Artículo en Inglés | MEDLINE | ID: covidwho-1469695

RESUMEN

OBJECTIVE: This study's main objective was to investigate the emergence of back pain as a consequence to changes in usual activities due to the COVID-19 pandemic among teachers in public schools in the state of Minas Gerais, Brazil. METHODS: A cross-sectional study was conducted among 15,276 schoolteachers using an online questionnaire. The variables included sociodemographic and occupational data, health situation, habits and behaviors during the COVID-19 pandemic. Bivariate analyses using Pearson's chi-square test and multiple analyses using Poisson regression were performed to identify the associated factors. RESULTS: About 58% of schoolteachers reported back pain due to changes in routine activities during the pandemic. The adjusted model showed a correlation between back pain and female sex, longer working hours, overwork, difficulties concerning distance working, negative changes in health status and quality of sleep; frequent feeling of sadness, depression, or anxiety; use of medications to relax, sleep or against stress/anxiety/depression; physical inactivity or negative changes in the practice of physical activities; increased body weight; reduction of leisure time; increased time of use of computer or tablet and overload of housework. CONCLUSION: During the COVID-19 pandemic, schoolteachers reported a high prevalence of emergence of back pain, which delineates a contradiction in terms: on the one hand, distance education allows social distancing that contributes to the preservation of teachers' health by reducing the risk of contamination by COVID-19. On the other hand, it imposes new demands that-in disagreement with working conditions-can threaten the health of these workers.


Asunto(s)
COVID-19 , Dolor de Espalda/epidemiología , Dolor de Espalda/etiología , Brasil/epidemiología , Estudios Transversales , Femenino , Humanos , Pandemias , SARS-CoV-2
5.
Curr Rheumatol Rep ; 23(8): 63, 2021 07 03.
Artículo en Inglés | MEDLINE | ID: covidwho-1293439

RESUMEN

PURPOSE: Myositis as a rare manifestation of COVID-19 is only recently being reported. This review examines the current literature on COVID-19-induced myositis focusing on etiopathogenesis, clinical presentations, diagnostic practices, and therapeutic challenges with immunosuppression, and the difficulties experienced by rheumatologists in established myositis in the COVID-19 era. RECENT FINDINGS: COVID-19 is associated with a viral myositis attributable to direct myocyte invasion or induction of autoimmunity. COVID-19-induced myositis may be varied in presentation, from typical dermatomyositis to rhabdomyolysis, and a paraspinal affliction with back pain. It may or may not present with acute exponential elevations of enzyme markers such as creatine kinase (CK). Virus-mediated muscle inflammation is attributed to ACE2 (angiotensin-converting enzyme) receptor-mediated direct entry and affliction of muscle fibers, leading on to innate and adaptive immune activation. A greater recognition of the stark similarity between anti-MDA5-positive myositis with COVID-19 has thrown researchers into the alley of exploration - finding common etiopathogenic basis as well as therapeutic strategies. For patients with established myositis, chronic care was disrupted during the pandemic with several logistic challenges and treatment dilemmas leading to high flare rates. Teleconsultation bridged the gap while ushering in an era of patient-led care with the digital transition to tools of remote disease assessment. COVID-19 has brought along greater insight into unique manifestations of COVID-19-related myositis, ranging from direct virus-induced muscle disease to triggered autoimmunity and other etiopathogenic links to explore. A remarkable shift in the means of delivering chronic care has led patients and caregivers worldwide to embrace a virtual shift with teleconsultation and opened doorways to a new era of patient-led care.


Asunto(s)
COVID-19/fisiopatología , Miositis/fisiopatología , Rabdomiólisis/fisiopatología , Inmunidad Adaptativa/inmunología , Enzima Convertidora de Angiotensina 2/metabolismo , Autoanticuerpos/inmunología , Dolor de Espalda/etiología , COVID-19/complicaciones , COVID-19/inmunología , COVID-19/metabolismo , Creatina Quinasa/metabolismo , Dermatomiositis/etiología , Dermatomiositis/inmunología , Dermatomiositis/metabolismo , Dermatomiositis/fisiopatología , Humanos , Inmunidad Innata/inmunología , Helicasa Inducida por Interferón IFIH1/inmunología , Miastenia Gravis/etiología , Miastenia Gravis/inmunología , Miastenia Gravis/metabolismo , Miastenia Gravis/fisiopatología , Miositis/etiología , Miositis/inmunología , Miositis/metabolismo , Músculos Paraespinales/fisiopatología , Receptores de Coronavirus/metabolismo , Rabdomiólisis/etiología , Rabdomiólisis/inmunología , Rabdomiólisis/metabolismo , SARS-CoV-2
6.
Rheumatol Int ; 41(7): 1263-1271, 2021 07.
Artículo en Inglés | MEDLINE | ID: covidwho-1224989

RESUMEN

To describe the rheumatic and musculoskeletal symptoms at hospitalization as well as their persistence/severity after discharge with coronavirus disease 2019 (COVID-19) and to identify whether age, sex, body mass index (BMI), and length of hospital stay are associated with persistence of these symptoms. In this single-center cohort study, comprising 300 participants, two phone interviews were conducted (2-week and 1-month after hospitalization) and symptoms were queried with a standardized form. This form included musculoskeletal symptoms and other COVID-19 symptoms. Considering all symptoms (musculoskeletal and other), 100.0%, 86.7%, and 72.0% of patients reported one or more symptoms, at hospitalization, 2-week, and 1-month, respectively. Considering only musculoskeletal symptoms, 92.3%, 72.7%, and 56.3% of patients reported any musculoskeletal symptom at hospitalization, 2-week, and 1-month, respectively. The musculoskeletal symptoms were fatigue (44.3% of patients reported), back pain (22.7%), arthralgia (22.0%), myalgia (21.0%), low back pain (16.3%), and neck pain (10.3%); the other symptoms were shortness of breath (26.3%), loss of taste (15.0%), cough (14.0%), loss of smell (12.3%), loss of appetite (10.3%), headache (8.7%), sore throat (3.0%), diarrhea (1.3%), dizziness (1.3%), and fever (0.3%) at 1-month. Increasing BMI was associated with higher odds of persistence of fatigue (OR: 1.08, 1.03 to 1.13), myalgia (OR: 1.08, 1.01 to 1.14), and arthralgia (OR: 1.07, 1.02 to 1.14, p = 0.012) at 1-month. Nearly three-quarters reported one or more symptoms, with more than half of patients reported any musculoskeletal symptom at 1 month. The most common musculoskeletal symptom was fatigue, followed by back pain, arthralgia, myalgia, low back pain, and neck pain. The persistence of fatigue, myalgia, and arthralgia was related to BMI. The study results increase our understanding of the spectrum of COVID-19, which, in turn, may lead to more efficient and better care for COVID-19 survivors.


Asunto(s)
Artralgia/etiología , Dolor de Espalda/etiología , COVID-19/complicaciones , Fatiga/etiología , Mialgia/etiología , SARS-CoV-2 , Adulto , Anciano , Femenino , Hospitalización , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Musculoesqueléticas , Alta del Paciente , Estudios Prospectivos
7.
BMJ Case Rep ; 14(3)2021 Mar 16.
Artículo en Inglés | MEDLINE | ID: covidwho-1138311

RESUMEN

We present a case of a giant ovarian cyst in a 20-year-old woman who presented atypically at our Emergency Department with left-sided back pain followed by acute left leg swelling. Blood tests showed significantly raised C-Reactive Protein and D-Dimer. CT-Abdomen-Pelvis demonstrated a large mass in the region of the right ovary with suspicious heterogeneous filling defects in the left external iliac vein, confirmed as a left-sided deep-vein thrombosis on ultrasound Doppler. MRI revealed the lesion to be cystic and the deep venous thrombosis was treated with twice-daily Clexane. Prior to removal of the cyst, an Inferior Vena Cava Filter was placed to reduce thromboembolic risk. The cyst was resected without complication and the postoperative period was uneventful. This case occurred while face-to-face services were limited by COVID-19 and illustrates the need for robust systemic measures to safeguard patients against the emergency sequelae of insidious gynaecological pathology.


Asunto(s)
Dolor de Espalda/etiología , Diagnóstico por Imagen/métodos , Quistes Ováricos/complicaciones , Quistes Ováricos/diagnóstico por imagen , Trombosis de la Vena/diagnóstico por imagen , Trombosis de la Vena/etiología , Adulto , Diagnóstico Diferencial , Enoxaparina/uso terapéutico , Femenino , Fibrinolíticos/uso terapéutico , Humanos , Pierna , Imagen por Resonancia Magnética , Quistes Ováricos/cirugía , Ovario/diagnóstico por imagen , Ovario/cirugía , Tomografía Computarizada por Rayos X , Ultrasonografía Doppler , Trombosis de la Vena/tratamiento farmacológico , Adulto Joven
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